Mediclinic Genetic Cardiovascular and Cancer Screening Packages

Genetic insights for lifelong protection

Your genes hold vital information that can shape a healthier future.
Mediclinic’s advanced genetic test screening packages help you understand your personalised risk of cardiovascular disease and inherited cancers, enabling smarter lifestyle decisions, proactive prevention and early intervention.

Genetic Counselling and Cardiovascular Panel Testing (AED 3,400)

A comprehensive genetic evaluation combining expert consultation with advanced Whole Exome Sequencing (WES). This package offers deep insight into the inherited and lifestyle-dependent factors that may affect your heart health.

• Consultation with a Clinical Geneticist
• Advanced cardiovascular panel testing using Whole Exome Sequencing (WES)
• Follow-up consultation to review results and provide a personalised treatment plan

The comprehensive panel analyses key genetic markers associated with cardiovascular diseases, enabling you to make informed decisions about your lifestyle and preventive care.

Most common conditions screened for are those that represent a major cause of sudden cardiac death. The majority of these disorders, when identified early, can be slowed down and managed accordingly:

Inherited high cholesterol/triglyceride/dyslipidemia (Familial Hypercholesterolemia)

A genetic condition that causes very high cholesterol levels from a young age. It raises the risk of early heart disease even in people who eat well and exercise.

Thickened heart muscle (Hypertrophic Cardiomyopathy) 
A hereditary condition in 50% of patients where the heart muscle becomes abnormally thick, making it harder for the heart to pump blood and sometimes causing chest pain, shortness of breath or fainting. During your consultation with the clinical geneticist, other causes related to this condition will be shared and investigated. 

Enlarged, weakened heart (Familial Dilated Cardiomyopathy)
An inherited problem in 50% of patients where the heart chambers stretch and weaken, reducing pumping strength and leading to tiredness, breathlessness or heart failure symptoms. During your consultation with the clinical geneticist, other causes related to this condition will be shared and investigated.

Heart rhythm reset problem (Long QT Syndrome, Burgada and CPVT)

A genetic electrical disorder that affects how the heartbeat resets after each beat, sometimes triggering dangerous irregular rhythms - especially during stress or exercise. Appropriate diagnosis leads to efficient medical treatment with significant best outcome.

Aortic Dissection (aortopathies)

A hereditary condition affecting the aorta, which can cause sudden aortic dissection and serious outcome. If diagnosed early can be managed accordingly.

Genetic Counselling and Cancer Panel Testing (AED 3,400)

An advanced screening package designed to assess your inherited risk of a wide range of cancers and multisystemic cancer-related conditions. Using Whole Exome Sequencing (WES), this panel provides a detailed genetic risk profile to support early detection and prevention strategies.

What’s included

• Consultation with a Clinical Geneticist
• Advanced cancer panel testing using Whole Exome Sequencing (WES)
• Follow-up consultation to review findings and outline a personalised prevention plan

We analyse the patient’s exome to assess inherited cancer risk across multiple systems, including:

Most commonly screened conditions are inherited and include:

• breast cancer risk
• ovarian cancer risk
• bowel cancer - Colorectal cancer
• Familial Adenomatous Polyposis
• uterine cancer (Endometrial cancer genes)
• stomach cancer (Gastric cancer)
• thyroid cancer (RET and other thyroid-related genes)
• pancreatic cancer risk
• prostate cancer
• skin cancer (Melanoma)
• Inherited kidney cancer (Renal cancer)

Cancer-related genetic syndromes:

• Lynch syndrome
• TP53 – Li Fraumeni
• Von Hippel Lindau
• Multiple Endocrine Neoplasia Syndrome
• Cowden Syndrome (PTEN Hamartoma Tumor Syndrome)
• Peutz-Jeghers Syndrome
• Retinoblastoma

What are genes?

Genes are segments of DNA that provide instructions for how your body grows, functions and maintains itself. All of a person’s genes together form the genome.
Some genes can develop mutations that may increase the risk of conditions such as cancers, tumours or inherited disorders.

• Dominant genes express their effects even if only one copy is present.
• Recessive genes require two copies of the mutation to cause disease—carriers often show no symptoms.

Understanding your genetic profile helps you anticipate health risks and make informed decisions about your future family.

What is Whole Exome Sequencing (WES)?

Whole Exome Sequencing analyses all the protein-coding parts of your genes, known as exons. Exons act as the body’s instruction manual—mutations in these regions can indicate a risk for hereditary diseases.

WES is particularly valuable in identifying recessive disease-causing variants, which may not affect the carrier but can pose a risk if both partners carry the same gene mutation. Identifying these risks early supports safe, informed reproductive planning.

Book your geneticist consultation via the Mediclinic app, call 800 2033 or fill in the form below.